Tetrapyrroles and derivatives
Abcam SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist, 10MG
MW 292.33 Da, Purity >99%. Potent and selective 5-HT2B and 5-HT2C serotonin receptor antagonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), 1A), 1D), 1E) and 1F). Centrally active following oral administration.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 500mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
eMolecules 42417-39-0 | 3-Aminodihydrofuran-2(3H)-one hydrochloride | MFCD27977179 | 1g
Ambeed | 5-Ethoxy-1H-indole-2-carboxylic acid | 250mg | 632809689 | A591873 | 93476-60-9 | MFCD02664445 | 205.213 | C11H11NO3
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Medchemexpress LLC Chlorin e6 trimethyl ester | 35038-32-5 | MFCD09838560 | 99.8% | 638.75 | C37H42N4O6 | 5 MG
Chlorin e6 trimethyl ester is a methyl pheophorbide-A derivative photosensitizer used in photodynamic therapy research and photophysics studies. It is supplied as a high-purity solid for in-vitro use and formulation, with defined solubility and storage recommendations to preserve stability.
- High reported purity (99.8%) suitable for research applications.
- Photosensitizer used in photodynamic therapy and photophysics studies.
- Soluble in DMSO at about 10 mg/mL with sonication and warming to 60°C; hygroscopic DMSO can affect solubility.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (6 months) or -20°C (1 month).
- Provided as a brown to black solid appropriate for formulation and analytical work.
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 100mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Sigma Aldrich Fine Chemicals Biosciences meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | 917-23-7 | MFCD00011680 | 1G
meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | Mol Wt: 614.74 | 917-23-7 | MFCD00011680 | 1G
Frontier Specialty Chemicals 10g meso-Tetra(4-pyridyl)porphine, 16834-13-2 MFCD00009626
meso-Tetra(4-pyridyl)porphine5,10,15,20-Tetra(4-pyridyl)-21H,23H-porphine CAS: 16834-13-2 MFCD00009626 Porphyrins Synthetic Porphyrins